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Rat Resource Database
Animal Model
动物模型的进步
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Accession No

Strain Name

Gene

Type

Disease & Phenotype

Status

GCNNNNN (编号)

SD(物种).Tg(转基因)gene(tm-定向突变)-GC/ILAS

基因名称

(简称)

Knockout/Knockin

/Transgene/spontaneous mutation

diseases/tool information

Live/cryopreservation

(状态)

GC00180

WISTAR.Tg(MHC-Cre)-Gc/ILAS

Cre

Knockin

Cre tool

Live

GC00179

WISTAR.Tg(UBC-Cre)-Gc/ILAS

Cre

Knockin

Cre tool

Live

GC00178

WISTAR.CRH(tm-Cre)-GC/ILAS

Cre

Knockin

Cre tool

Live

GC00177

WISTAR.AVP(tm-Cre)-GC/ILAS

Cre

Knockin

Cre tool

Live

GC00176

WISTAR.PVALB(tm-Cre)-GC/ILAS

Cre

Knockin

Cre tool

Live

GC00175

WIATAR.Rosa26(tm-imCherry)-GC/ILAS

Cre reporter

Knockin

Cre reporter

Live

GC00174

WISTAR.POMC(tm-Cre)-GC/ILAS

Cre

Knockin

Cre tool

Live

GC00173

WISTAR.LOC1009A

(tm-Cre)-GC/ILAS

Cre

Knockin

Cre tool

Live

GC00172

WISTAR.APOA4

(tm-Cre)-GC/ILAS

Cre

Knockin

Cre tool

Live

GC00171

WISTAR.CYP2E1

(tm-Cre)-GC/ILAS

Cre

Knockin

Cre tool

Live

GC00170

SD. Isca1 (tm-loxp)

-GC/ILAS

Isca1

conditional knockout

 

Live

GC00169

SD.Camk2a(tm-Cre)

-GC/ILAS

Camk2a

Knockin

 

Live

GC00168

SD.Tbr1(tm-Cre)

-GC/ILAS

Tbr1

Knockin

 

Live

GC00167

SD.Dlg3(tm-Cre)

-GC/ILAS

Dlg3

Knockin

 

Live

GC00166

SD.Synpr(tm-Cre)

-GC/ILAS

Synpr

Knockin

 

Live

GC00165

SD. GBAS (tm-loxp)

-GC/ILAS

GBAS

conditional knockout

 

Live

GC00164

SD. CST7 (TM )

-GC/ILAS

CST7

knockout

 

Live

GC00163

WISTAR.Prkdc(tm)

-GC/ILAS

Prkdc

Knockout

immune system diseases

Freezed embryo

GC00162

SD. ALDH1L1 (TM-cre)-GC/ILAS

Aldh1l1

knockin

 

Live

GC00161

SD. FAM109A 

 (TM- LOXP)-GC/ILAS

FAM109A

conditional knockout

 

Live

GC00160

SD. FAM109A (TM)

-GC/ILAS

FAM109A

Knockout

 

Live

GC00159

SD. TMEM119 (TM)

-GC/ILAS

TMEM119

Knockout

 

Live

GC00158

SD. Reelin (tm-Cre)

-GC/ILAS

REELIN

knockin

 

Live

GC00157

SD. TRIM46 

 (TM- LOXP)-GC/ILAS

TRIM46

conditional knockout

 

Live

GC00156

SD. TRIM44 

 (TM- LOXP)-GC/ILAS

TRIM44

conditional knockout

 

Live

GC00155

SD. GBAS (tm)

-GC/ILAS

GBAS

knockout

 

Live

GC00154

SD. SF3B6 (tm-LOXP )

-GC/ILAS

SF3B6

conditional knockout

 

Live

GC00153

SD. CYP2E1 (tm)

-GC/ILAS

CYP2E1

Knockout

 

Live

GC00152

SD. GAD1 (tm-Cre)

-GC/ILAS

GAD1

Knockin

 

Live

GC00151

SD.Olig2(tm-Cre)-GC/ILAS

Olig2

Knockin

 

Live

GC00150

SD.Trdmt1(tm)-GC/ILAS

Dnmt2

Knockout

 

Live

GC00149

WISTAR.IFNr (tm )

-GC/ILAS

 

knockout

 

Freezed embryo

GC00148

SD.Dcx(tm-Cre)

-GC/ILAS

Dcx

Knockin

 

Live

GC00147

SD.Pax6(tm-Cre)

-GC/ILAS

Pax6

Knockin

 

Live

GC00146

SD.S100a4(tm-Cre)

-GC/ILAS

S100a4

Knockin

 

Live

GC00145

SD.Pnoc(tm-Cre)

-GC/ILAS

Pnoc

Knockin

 

Live

GC00144

SD.Cxcl14(tm-Cre)

-GC/ILAS

Cxcl14

Knockin

 

Live

GC00143

SD.Gda(tm-Cre)-GC/ILAS

Gda

Knockin

 

Live

GC00142

SD.Mbp(tm-Cre)-GC/ILAS

Mbp

Knockin

 

Live

GC00141

SD.latexin(tm-Cre)-GC/ILAS

latexin(Lxn)

Knockin

 

Live

GC00140

SD.Drd3(tm-Cre)-GC/ILAS

Drd3

Knockin

 

Live

GC00139

SD.Gng2(tm-Cre)-GC/ILAS

Gng2

Knockin

 

Live

GC00138

SD.Spink8(tm-Cre)

-GC/ILAS

Spink8

Knockin

 

Live

GC00137

SD.Lypd1(tm-Cre)

-GC/ILAS

Lypd1

Knockin

 

Live

GC00136

SD.Dbndd1(tm-Cre)

-GC/ILAS

Dbndd1

Knockin

 

Live

GC00135

SD.Cux2(tm-Cre)-GC/ILAS

Cux2

Knockin

 

Live

GC00134

SD.NeuN(tm-Cre)-GC/ILAS

NeuN(Rbfox3)

Knockin

 

Live

GC00133

SD.Sst(tm-Cre)-GC/ILAS

Sst

Knockin

 

Live

GC00132

SD.Vglut3(tm-Cre)-GC/ILAS

Vglut3Slc17a8

Knockin

 

Live

GC00131

SD.Npy(tm-Cre)-GC/ILAS

Npy

Knockin

 

Live

GC00130

SD.Nkx2-1(tm-Cre)-GC/ILAS

Nkx2-1

Knockin

 

Live

GC00129

SD.Vip(tm-Cre)-GC/ILAS

Vip

Knockin

 

Live

GC00128

SD. CACNB2 (C.1515-1516 ins CGCTC )-GC/ILAS

CACNB2

mutation

 

Freezed embryo

GC00127

SD. VGAT (TM-CRE )-GC/ILAS

 

knockin

 

Live

GC00126

SD. SLC41A2 (TM-LOXP)-GC/ILAS

Slc41a2

conditional knockout

 

Freezed embryo

GC00125

SD.Sst(tm)-GC/ILAS

Sst

Knockin

 

Live

GC00124

SD.DNMT2(TM-mcherry) -GC/ILAS

Dnmt2

Knockin

 

Live

GC00123

SD. CST7 (TM-LOXP )-GC/ILAS

CST7

conditional knockout

 

Live

GC00122

SD. ADTRP (TM )-GC/ILAS

ADTRP

knockout

 

Live

GC00121

SD. SLC41A2 (TM)-GC/ILAS

Slc41a2

conditional knockout

 

Live

GC00120

SD. COl5a2 (TM-LOXP )-GC/ILAS

Col5a2

conditional knockout

 

Live

GC00119

SD. ADTRP (TM-LOXP )-GC/ILAS

ADTRP

conditional knockout

 

Live

GC00118

SD.ABCB1a&1b(tm) -GC/ILAS

Abcb1a Abcb1b

knockout

 

Freezed embryo

GC00117

SD.PCP4(tm) -GC/ILAS

Pcp4

knockout

 

Freezed embryo

GC00116

SD.SLC6A6(tm) -GC/ILAS

Slc6a6

knockout

 

Freezed embryo

GC00115

SD.ALDH1L1(tm) -GC/ILAS

Aldh1l1

knockout

 

Freezed embryo

GC00114

SD.RGS14(tm) -GC/ILAS

Rgs14

knockout

 

Freezed embryo

GC00113

SD.VIP(tm) -GC/ILAS

VIP

knockout

 

Freezed embryo

GC00112

SD.ISCA1(tm-mcherry-Cre)-GC/ILAS

Isca1

Knockin

 

Live

GC00111

WISTAR.Vglut3(tm-Cre )-GC/ILAS

Vglut3

knockout

 

Freezed embryo

GC00110

WISTAR.IL2rg (tm )-GC/ILAS

IL2rg

knockout

 

Freezed embryo

GC00109

SD.Mef2c(tm )-GC/ILAS

Mef2c myocyte enhancer factor 2C

 

 

Freezed embryo

GC00108

SD.Alb(tm-Cre) -GC/ILAS

Cre insertion at Alb locus

knockin

 

Live

GC00107

SD.Nkx2.1(tm) -GC/ILAS

Nkx2.1

knockout

 

Live

GC00106

SD.Tg(Alb-Cre) -GC/ILAS

Alb-Cre

transgene

 

Freezed embryo

GC00105

SD.Tg(α-MHC-H-Dhcr24) -GC/ILAS

H-Dhcr24

transgene

 

Freezed embryo

GC00104

SD.Dhcr24(tm-loxP)- GC/ILAS

Dhcr24

conditional knockout

 

Freezed embryo

GC00103

SD.Isca1MagR(tm)-GC/ILAS

Isca1

knockout

 

Freezed embryo

GC00102

SD. Rosa26(tm-imCherry)-GC/ILAS

knockin Cre reporter cassette into Rosa26 locus

 

 

Live

GC00101

SD.Wfs1(tm)-GC/ILAS

Wfs1

Knock out

 

Freezed embryo

GC00100

SD.Cyp3A(a9-a62)(tm)-GC/ILAS

Cyp3A

knockout (A9-A62)

 

Freezed embryo

GC00099

SD. Mybpc3(tm-c.3293G>A)-GC/ILAS

Mybpc3

mutation

 

Freezed embryo

GC00098

SD. Ttn(tm-c.58880 ins A)-GC/ILAS

Ttn

mutation

 

Freezed embryo

GC00097

SD. Ttn(tm-c.1390C>T)-GC/ILAS

Ttn

mutation

 

Freezed embryo

GC00096

SD.CYP3A(a1/a2) (tm)-GC/ILAS

CYP3A(a1/a2)

Knockout

 

Freezed embryo

GC00095

SD. Cplx1(tm)-GC/ILAS

Cplx1

Knock out

 

Freezed embryo

GC00094

SD. Myh7(tm-c.1357C>T)-GC/ILAS

Myh7

mutation

 

Freezed embryo

GC00093

SD.Defb26(tm)-GC/ILAS

Defb26

Knock out

 

Freezed embryo

GC00092

SD.Defb23(tm)-GC/ILAS

Defb23

Knock out

 

Freezed embryo

GC00091

SD.Cyp3A(a1-a2)(tm)-GC/ILAS

 

 

 

Freezed embryo

GC00090

SD.Cyp3A(a1-a18)(tm)-GC/ILAS

 

 

 

Freezed embryo

GC00089

SD.Ephb4(tm-loxP)-GC/ILAS

Ephb4

conditional knockout

 

Live

GC00088

SD.Tg(CAG-Cre)-GC/ILAS

 

 

 

Freezed embryo

GC00087

SD.Pirt(tm-Cre)-GC/ILAS

Pirt

knockin

 

Freezed embryo

GC00086

SD.Ndst4(tm)-GC/ILAS

Ndst4

Knockout

 

Freezed embryo

GC00085

SD. Myh7b (tm-c.5612-5613GC>CT)-GC/ILAS

Myh7b

mutation

 

Freezed embryo

GC00084

SD.C9orf72(tm-eGFP)-GC/ILAS

 

 

 

Live

GC00083

SD.miR451a(tm)-GC/ILAS

Mir451a

mutation

 

Freezed embryo

GC00082

SD.Pou3f4(tm-Cre)-GC/ILAS

Pou3f4

Knockin

 

Live

GC00081

SD. NeuN(tm-CreERT2)-GC/ILAS

Rbfox3(NeuN)

knockin

 

Freezed embryo

GC00080

SD. Rosa26(tm-iNTR)-GC/ILAS

 

 

 

Freezed embryo

GC00079

SD. Vglut3(tm)-GC/ILAS

Vglut3

Knockout

 

Freezed embryo

GC00078

SD. NeuN(tm)-GC/ILAS

NEUN

Knockout

 

Freezed embryo

GC00077

SD. Latexin(tm)-GC/ILAS

latexin

Knockout

 

Freezed embryo

GC00076

SD. Gdi(tm)-GC/ILAS

GID

Knockout

 

Freezed embryo

GC00075

SD.Cox5a(tm)-GC/ILAS

Cox5a

Knockout

 

Freezed embryo

GC00074

SD.Pnpla5(tm)-GC/ILAS

Pnpla5

Knockout

 

Freezed embryo

GC00073

SD. wfs1(tm- Cre)-GC/ILAS

Wfs1

knockin

 

live

GC00072

SD. Ndst4(tm- Cre)-GC/ILAS

Ndst4

knockin

 

live

GC00071

SD. Dbndd1(tm- CreERT2)-GC/ILAS

Dbndd1

knockin

 

Freezed embryo

GC00070

SD. GFAP(tm- CreERT2)-GC/ILAS

GFAP

knockin

 

Freezed embryo

GC00069

CYP3a1/ CYP3a2

 

Knockout

 

Freezed embryo

GC00068

CYP3a2

 

Knockout

 

Freezed embryo

GC00067

SD. CYP3a1 (tm)-GC/ILAS

CYP3a1

knockout

 

Freezed embryo

GC00066

SD.FabP2(tm-Cre)-GC/ILAS

FabP2Cre

Knockin

FabP2 induced gene knockout

Freezed embryo

GC00065

SD.Sox2(tm-CreERT2)-GC/ILAS

Sox2Cre

Knockin

CreSox2 induced gene knockout

Freezed embryo

GC00064

SD.Tg(UBC-Cre)-Gc/ILAS

UBC

Transgene

Cre whole body

Live

GC00063

SD.Nes(tm-CreERT2)-GC/ILAS

Nes/Cre

Knockin

CreNeuron induced gene knockout

Freezed embryo

GC00062

SD.Gp130(tm-loxp)-GC/ILAS

GP130IL6ST

conditional knockout

IL6CT1 LIF co-receptor

Freezed embryo

GC00061

SD.Gp130(tm)-GC/ILAS

GP130IL6ST

Knockout

IL6CT1 LIF co-receptor

Freezed embryo

GC00060

SD.Tg(BAC-h-Cyp3a)-GC/ILAS

hCyp3a

Transgene

drug metabolismtoxicity

Freezed embryo

GC00059

SD.Rag2(tm)-GC/ILAS

Rag2

Knockout

immune system diseases

Freezed embryo

GC00058

SD.Pon1(tm)-GC/ILAS

Pon1

knockout

 

Live

GC00057

SD.Tg(BAC-h-DNMT3A)-GC/ILAS

hDNMT3A

Transgene

 

Freezed embryo

GC00056

SD.Mir29a&29b-1(tm)-GC/ILAS

Mir29a&29b-1

Knockout

fibrosis heart liver kidney

Freezed embryo

GC00055

SD.Mir29a(tm)-GC/ILAS

Mir29a

Knockout

fibrosis heart liver kidney

Live

GC00054

SHRSP/OLA rat

 

inbred strain

hypertension

Freezed embryo

GC00053

R3R12

 

Congenic Inbred Strain

 

Freezed embryo

GC00052

R3R6

 

Congenic Inbred Strain

 

Freezed embryo

GC00051

Dark Agouti RatDA Rat

 

inbred strain

 

Freezed embryo

GC00050

RCS

 

Inbred strain

Retinal degneration

Freezed embryo

GC00049

SD.Tg(BAC-h-DNMT3B)-GC/ILAS

hDNMT3B

Transgene

 

Freezed embryo

GC00048

SS-Tg(ApoC3-CETP)53Opaz

human CETP cDNA

transgene

hypercholesterolemia, hypertriglyceridemia, low HDL, coronary atherosclerosis

Freezed embryo

GC00047

SD.Pou3f1(tm-Cre)-GC/ILAS

Pou3f1

Knockin

 

Live

GC00046

SD.Tg(HBV1.3)-GC/ILAS

HBV

Transgene

Hepatitis

Freezed embryo

GC00045

SD.Tg(CAG-RFP)-GC/ILAS

RFP

Transgene

DsRed labling

Freezed embryo

GC00044

SD.Tg-PBase-GC/ILAS

PBase, prm1

Transgene

transposon system

Freezed embryo

GC00043

SD.Tg-PBSBD-GC/ILAS

PBSBD

Transgene

transposon system

cryopreservation

GC00042

SD.Tg(Prp-PS1dE9)-GC/ILAS

PS1dE9

Transgene

Alzheimer's disease

Freezed embryo

GC00041

SD.Tg(BAC-h-DNMT1)-GC/ILAS

hDNMT1

Transgene

 

Freezed embryo

GC00040

SD.Tg(Prp-APPswe/PS1dE9 PDGF-TAU)

APP swePS1 dE9TAU

Transgene

Alzheimer's disease

Freezed embryo

GC00039

SD.Tg(a-MHC-a-synuclein WT)-GC/ILAS

SNCA

transgene

no significant phenotype

Freezed embryo

GC00038

SD.Tg(a-MHC-a-synuclein A53T)-GC/ILAS

SNCA

Transgene

heart disease

Freezed embryo

GC00037

SD.Tg(PDGF-a-synuclein A53T)-GC/ILAS

SNCA

Transgene

Parkson's disease

Freezed embryo

GC00036

SD.Tg(CAG-GFP)-GC/ILAS

eGFP

Transgene

GFP labling

Freezed embryo

GC00035

SD.Tg(PDGF-CRE)-GC/ILAS

Cre

Transgene

Neuron, Cre

Freezed embryo

GC00034

SD.Tg(MHC-CRE)-GC/ILAS

MHC-CRE

Transgene

heart, Cre

Freezed embryo

GC00033

SD.Nes(tm)-GC/ILAS

Nes

Knockout

Neuron Stem cell

Freezed embryo

GC00032

SD.Nes(tm-Cre)-GC/ILAS

NES Cre

Knockin

Neuron Stem cellCre

Freezed embryo

GC00031

SD.Cck(tm)-GC/ILAS

Cck

Knockout

Brain gut, pain, food uptake

Freezed embryo

GC00030

SD.Cck(tm-Cre)-GC/ILAS

Cck, Cre

Knockin

CrebrainBraingut, pain, food uptake

Live

GC00029

SD.Dnmt3L(tm-loxp)-GC/ILAS

Dnmt3L

conditional knockout

DNA methylation

Freezed embryo

GC00028

SD.Dnmt3L(tm)-GC/ILAS

Dnmt3L

Knockout

DNA methylation

Freezed embryo

GC00027

SD.Dnmt3B(tm-loxp)-GC/ILAS

Dnmt3B

conditional knockout

DNA methylation

Freezed embryo

GC00026

SD.Dnmt3B(tm)-GC/ILAS

Dnmt3B

Knockout

DNA methylation

Freezed embryo

GC00025

SD.Dnmt3A(tm-loxp)-GC/ILAS

Dnmt3A

conditional knockout

DNA methylation

Freezed embryo

GC00024

SD.Tg(BAC-h-Trdmt1)-GC/ILAS

hDNMT1

Transgene

 

Freezed embryo

GC00023

SD.Dnmt3A(tm)-GC/ILAS

Dnmt3A

Knockout

DNA methylation

Freezed embryo

GC00022

SD.Trdmt1(tm-gfp)-GC/ILAS

Trdmt1 Dnmt2

Knockin

Epigenetics

Freezed embryo

GC00021

SD.Dnmt1(tm-loxp)-GC/ILAS

Dnmt1

conditional knockout

DNAmethylation

Live

GC00020

SD.Dnmt1(tm)-GC/ILAS

Dnmt1

Knockout

Epigenetics

Freezed embryo

GC00019

SD.Tg(ALB-NTCP)-Gc/ILAS

NTCP

Transgene

liver

Freezed embryo

GC00018

SD.Pparg(tm)-GC/ILAS

PPARG

Knockout

metabolic disease

Freezed embryo

GC00017

SD.NTCP(tm)-GC/ILAS

NTCP

Knockout

liver diseases

Freezed embryo

GC00016

SD.Tg(BAC-h-Nr1i2)-GC/ILAS

h-Nr1i2(Pxr)

Transgene

drug metabolism

Freezed embryo

GC00015

SD.Tg(BAC-h-Ahr)-GC/ILAS

h-Ahr

Transgene

drug metabolismtoxicity

Freezed embryo

GC00014

SD.Tg(BAC-h-Abcb1)-GC/ILAS

h-Abcb1(Mdr1)

Transgene

drug metabolism

Freezed embryo

GC00013

SD.Ucp1(tm)-GC/ILAS

UCP1

Knockout

lipid metabolismobesity, diabetes

Freezed embryo

GC00012

SD.B2m(tm)-GC/ILAS

B2m

Knockout

immunetransplantation

Freezed embryo

GC00011

SD.Prf1(tm)-GC/ILAS

Prf1PFP

Knockout

immune system diseases

Freezed embryo

GC00010

SD.Prkdc(tm)-GC/ILAS

Prkdc

Knockout

immune system diseases

Freezed embryo

GC00009

SD.Lepr(tm)-GC/ILAS

Lepr

Knockout

lipid metabolismobesity, diabetes

Live

GC00008

SD.Nr1i2(tm)-GC/ILAS

rNr1i2(Pxr)

Knockout

drug metabolism

Freezed embryo

GC00007

SD.Ahr(tm)-GC/ILAS

AHR

Knockout

drug metabolism toxicity

Freezed embryo

GC00006

SD.Abcb1(tm)-GC/ILAS

ABCB11 MDR1

Knockout

drug metabolismdrugresistance toxicity

Freezed embryo

GC00005

SD.Apoe(tm)-GC/ILAS

ApoE

Knockout

Neurological diseases

Freezed embryo

GC00004

SD.Foxo3(tm)-GC/ILAS

Foxo3

Knockout

cell cycle, stress, apoptosis

Freezed embryo

GC00003

SD.Irs1(tm)-GC/ILAS

Irs1

Knockout

glycometabolismdiabetes

Freezed embryo

GC00002

SD.Ctf1(tm)-GC/ILAS

Ctf1

Knockout

nervous system disease

Freezed embryo

GC00001

SD.Lep(tm)-GC/ILAS

Lep

Knockout

lipid metabolism, obesity, diabetes

Freezed embryo

地   址:北京市朝阳区潘家园南里5号(中国医学科学院医学实验动物研究所)

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