新闻资讯

以真诚努力,服务医学进步

GC00023

来源: 作者: 发布时间: 2021-05-08 433 次浏览

Accession No

GC00023

Strain Name

SD.Dnmt3A(tm)-GC/ILAS

Status

Freezed embryo

Gene/full name

Dnmt3a / DNA methyltransferase 3 alpha

Gene ID

444984

Background

Sprague Dawley

Type

Knockout

Donor

Lianfeng Zhang, Yuanwu Ma , Xu Zhang, Wei Chen

Disease & Phenotype

DNAmethylation

Construction Description

Genotyping Protocols

DNMT3a-loxp-F  TGAGGACAGATTAGAAGGAAAATG  

DNMT3a-loxp-R  ACAGTGGTTATAGGTATGGTGGTG

 

Mating System

Heterozygote x Heterozygote;

 

Reference

 

1. Yuanwu Ma , Xu Zhang , Bin Shen. Generating rats with conditional alleles using  CRISPR/Cas9, Cell Research. 2014.