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GC00020

来源: 作者: 发布时间: 2021-05-08 413 次浏览

Accession No

GC00020

Strain Name

SD.Dnmt1(tm)-GC/ILAS

Status

Freezed embryo

Gene/full name

Dnmt1/ DNA methyltransferase 1

Gene ID

84350

Background

Sprague Dawley

Type

Knockout

Donor

Lianfeng Zhang, Yuanwu Ma , Xu Zhang, Wei Chen

Disease & Phenotype

Epigenetics

 

Construction Description

 

Genotyping Protocols

DNMT1-loxp-F   GTGCCCATAGAGACCAGAAGAG   

DNMT1-loxp-R   AGATACCCCAATAAATGCCTCC

 

Mating System

Heterozygote x Heterozygote;

 

Reference

 

1. Yuanwu Ma , Xu Zhang , Bin Shen. Generating rats with conditional alleles using  CRISPR/Cas9, Cell Research. 2014.